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BRAVO. What a BEAUTIFUL campaign, with an extraordinary amount of variety to the setting that all somehow tied together still. I also love the alternate routes offered--it makes replayability a sure-thing. —Michael (on the L4D Mailing List)

Archive for December, 2010

Dec24

Christmas news

Posted by Geoffroy in Media, Progress

rpk-tramplin

Calculations suggest NFL Jerseys China that about 9 million cubic metres of magma 3,600 Olympic swimming pools’ worth pushed into the crust each year during peak growth. The molten rock would have gathered in a chamber about 10 kilometres below the surface. “When you compare it to other places, like Yellowstone, we’re smaller than that,” Hamling says. “But it’s still pretty significant.”Isolated PSC Cholangiocytes Exhibit Abnormal Cell Morphology and Impaired Epithelial JunctionsWe next assessed morphological characteristics of isolated PSC cholangiocytes compared with NHCs. Compared with NHCs (Figure 2a), we found that isolated PSC cholangiocytes (Figure 2b) exhibit multiple distinguishing features, including enlarged size and robust filamentous (cytoskeletal) structures throughout the cell body. Given these differences, we next assessed whether isolated PSC cholangiocytes achieve Authentic NFL Jerseys the same level of ZO1 tight junction protein expression. Based on ZO1 immunofluorescence Replica Oakleys staining, we found that PSC cholangiocytes express Replica Oakley Sunglasses less ZO1 protein compared with normal cholangiocytes (Figure 2c). Moreover, based on TEER readings between days 2 and 5 post plating, we found resistance to be significantly lower (P in isolated PSC compared with normal cholangiocytes (Figure 2c). (a) Confluent normal human cholangiocyte (NHC) cell line form a tight monolayer after 7 days in culture, as compared with isolated PSC cholangiocytes (b), which are slow to become confluent after 7 days in culture and appear irregular and larger in size as compared with NHCs (both 20 magnification). (c) Cultured NHCs form tight junctions with neighboring cells, as indicated by expression of tight junction marker, Z01 (green), whereas cultured PSC cholangiocytes display fewer than normal tight junctions between cells as indicated by decreased ZO1 expression. (d) Transepithelial electrical resistance (TEER) was measured in normal cholangiocytes, H69 and NHC, and isolated PSC cholangiocytes to determine formation and integrity of tight junctions between cells. Isolated PSC cholangiocytes exhibit significantly lower TEER readings compared with both H69 and NHC cell lines cheap jerseys from days 2 to 5 (P indicating impaired tight junctions in the former.In 1993, after losing 11 of their first 12 games, the team won the last 4 games. Interest in the Patriots was high. In early 1994, Orthwein attempted to Baratas Replicas Ray Ban clear the hurdles to move the team to St Louis. But the stadium owner, cheap jerseys Bob Kraft, refused to let the Patriots out of their lease. Orthwein became frustrated and put the franchise up for sale. Kraft bought it for a whopping $175 million.
Dec8

Moddb 2010 (Top100) and news summary

Posted by Geoffroy in General, Progress

With the help of your votes, I hate mountains has been picked from the Moddb top 100 mods of the year. We thank your sincerely for you support. If you want to continue to help us, please vote once again for IHM and bring it on the top 15 !vian34

Click on the banner and vote on the next page, it’s free and you don’t have to register ! Feel free to share it on Facebook or Twitter on the next page too.

Beside that, just as we tweet few days ago, we built a release canditate for the l4d2 version of IHM. We also found a french gaming team which accepted to test and provide rigorous feedbacks. It should allow us to find out any missed bugs and solve them. Actually, we already fixed a lot of thing with the help of these french guys, even some unusual and outstanding exploits !

Finally, The most annoying thing is that the support of custom particles has been unfortunatly broken by Valve since the release of their last DLC “the Sacrifice”. We sincerely hope they will fix this before our release, but if this is not the case, we’ll do without it. Anyway, our custom particles should be packaged in the vpk, hoping that an upcoming update could fix this.

At last, we planned to release both version ( l4d 1.2 version and l4d2 version) this December, as soon as we finished playtests and corrections.

Until this, stay tuned ;)

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